Roger Martin Denome
Personal
Roger Martin Denome
Associate Professor of Biology
213 Science Building
Stonehill College
320 Washington St.
Easton, MA 02357 (508) 565 1196 rdenome@stonehill.edu
EDUCATION
Postdoctoral studies, 1985-1989, Department of Biochemistry,
Dartmouth Medical School, Hanover, New Hampshire 03756
Ph.D. in Genetics, August 1985, Michigan State University, East Lansing, Michigan 48824. Dissertation title: Identification and Characterization of the Nuclear RNA Trafficking Pattern in Normal and Adenovirus-infected Cells.
B.S. in Zoology, June 1979, Michigan State University,
East Lansing, Michigan 48824
TEACHING EXPERIENCE
Full-time Appointments
Stonehill College Associate Professor September 1996-Present
University of North Dakota (UND) Assistant Professor September 1989-May 1996
Courses Taught
Genetics (Stonehill and UND)
Molecular Biology (Stonehill and UND)
Virology (Stonehill)
Seminar in Genetics of Human Disease (Stonehill)
Scientific Critique (Stonehill)
Introductory Biology for Majors (UND)
Introductory Biology for Non-majors (UND)
The sword cuts both ways: ethical dilemmas caused by advances in biology (Stonehill, through Continuing Education program)
Evolution (Stonehill, through Continuing Education program)
Independent and Directed studies
Research at Stonehill includes the name of student(s), the title of the project, the program in which the research was done [Stonehill Undergraduate Research Experience (SURE) or directed study (ds)], and the period of time over which the research extended. In addition, the names of the students who worked with me during my last 3 years at UND are included.
Stonehill College
Adam Silver
Population genetics of Cape Cod coyotes [Fall, Spring 2000-1, (ds)]
Katie MacAfee
Gene Expression Patterns in Aging C. elegans [Fall 2000 (ds)]
Robin Milley, Sara Swan, Lynn Avezzie
Molecular Biology of Thompson Island Skunks[Summer 2000 (SURE, S.S., R.M.), Fall 2000 (ds, R.M., L.A.)]
Ana Abujamra, Emily Hart, Coreen Beaumier
Molecular Population genetics of dog ticks and their pathogens [Fall 1999 (ds, AA., E.H.), Spring 2000 (ds, C.B.)].
Dennis O'Brien
Molecular Population genetics of Thompson Island Skunks [Fall 1999 (ds)].
Ernest LaCroix
Molecular Population genetics of Massachusetts Coyotes [Fall 1999 (ds)].
Rebecca Coburn, Erin Lutynski
Molecular Population genetics of Massachusetts Coyotes [Summer 1999 (SURE), Fall 1999 (ds)].
Suzanne McIntyre
Analysis of Genetic Variation in Ladybird Beetles [Spring 1999, (ds)].
Jennifer Demoranville
Molecular Population Genetics of Massachusetts Coyotes [Spring 1999, (ds)].
Kelly Gillick
Molecular Population Genetics of Striped Skunks in Eastern Massachusetts [Fall 1998, (ds)].
Jenifer Gilbert, Tamara Palka
Molecular Population Genetics of Utah Mule Deer [Summer 1998, (SURE, J.G., T.P.), Fall 1998, (ds, T.P.)].
Matt Barth, Jessica Maheux
Molecular Population Genetics of White Tail Deer from Eastern North America [Summer 1998 (SURE, M.B., J.M.), Fall 1998, (ds, J.M.)].
Nathaniel Poulin
Isolation and Characterization of Plasmids from Wild Bacteria [Spring 1998, (ds)].
Paula Famolare
A Molecular Pedigree of an Extended Human Family [Spring 1998, (ds)].
Lisa Carvalho
Molecular Phylogenetic Studies of Orchids [Fall 1997, (ds)].
Audra Beede
Computer Models for Population Genetics Education [Fall 1997, (ds)].
Adrienne O'Connell
Molecular Population Genetics using DNA from antler [Summer 1997, (SURE), Fall 1998 (ds)].
Nathaniel Poulin
Assays of Genetic Variation in an Isolated Population of Utah Elk [Summer 1997, (SURE)].
Allison Morse
Assays of Genetic Variation in Honey Mushrooms [Spring 1997, (ds)].
Lisa Carvalho
Are Manitoba Elk a Separate Subspecies? [Summer 1997, (SURE)].
Laura Carvalho
Phylogenetic Relationships Among Ungulates [Summer 1997 (SURE) and Fall 1997 (ds)].
Laura Carvalho and Lisa Carvalho
Genetic variation and differentiation in Rocky Mountain Bighorn sheep in Eastern Utah [Spring 1997, ds].
University of North Dakota Students, 1994-1996.
Masters degree students
Christopher Fischer, Brennon O'Callaghan.
Undergraduates
Robert Bianco, Jennifer Butler, Elizabeth Harper, Cameron Luitjens, Cassandra Pederson, Jodi Perry, Faye Person, Venera Radu, Patty Szczys.
SCHOLARSHIP AND CREATIVE WORK
Contributions
Publications
1. O'Connell, A., and R. M. Denome. 1999. Microsatellite Locus amplification using deer antler DNA. Biotechniques 26:1086-1088
2. Denome, R.M. 1997. A Synopsis of Genetics. Wm. C. Brown, Dubuque, IA
3. Denome, R. M., B. O'Callaghan, C. Luitjens, E. Harper, B. Bianco. 1994. Characterization of a satellite DNA from Antilocapra americana. Gene 145:257-259.
4. Heath, C. V., R. M. Denome, and C. N. Cole. 1990. Spatial constraints on polyadenylation signal function. J. Biol. Chem. 256(16):9098-9104.
5. Denome, R. M., E. W. Werner, and R. J. Patterson. 1989. RNA metabolism in nuclei: adenovirus and heat shock alter intranuclear RNA compartmentalization. Nucleic Acids Research 17:2081-2098.
6. Denome, R. M., and C. N. Cole. 1988. Patterns of polyadenylation site selection in gene constructs containing multiple polyadenylation signals. 1988. Mol. Cel. Biol. 8:4829-4839.
7. Zhang, F., R. M. Denome and C. N. Cole. 1986. Fine structure analysis of the processing and polyadenylation region of the Herpes simplex virus type I thymidine kinase gene by using linker scanning, internal deletion, and insertion mutants. Mol. Cel. Biol. 6:4611-4623.
8. Seki, T., T. Moriuchi, H.-C. Chang, R. M. Denome, and J. Silver. 1985. Structural organization of the rat Thy-1 gene. Nature 313: 485-487.
9. Seki, T., H.-C. Chang, T. Moriuchi, R. M. Denome, H. Ploegh, and J. Silver. 1985. A hydrophobic transmembrane segment at the carboxyl terminus of Thy-1. Science 227:649-651.
10. Seki, T., T. Moriuchi, H.-C. Chang, R. M. Denome, and J. Silver. 1985. Thy-1: a hydrophobic transmembrane segment at the carboxyl terminus. Fed. Proc. 44:2865-2869
11. Young, R. B., and R. M. Denome. 1984. Effect of creatine on content of myosin heavy chain and myosin-heavy-chain mRNA in steady-state chicken muscle-cell cultures. Biochemical J. 218:871-876.
12. Moriuchi, T., H.-C. Chang, R. M. Denome, and J. Silver. 1983. Thy-1 cDNA sequence suggests novel regulatory mechanism. Nature 301:80-82.
13. Young, R. B., R. M. Denome, and G. W. Achtymichuk. 1981. Stimulation of myosin heavy chain synthesis in steady-state muscle cultures by the ionophore, A23187, requires transcription of messenger RNA. Eur. J. Cell Bio. 26:184-187.
Abstracts presented at meetings
1. Becky Coburn, Erin Lutynski and Roger Denome. 1999 Assays of genetic variation in coyotes in Massachusetts. Pfizer Undergraduate research symposium. October 8, 1999, Groton, Connecticut.
2. Tamara J. Palka, Jenifer Gilbert, and Roger Denome. 1999 Genetic Variation and Population Mixing in Mule Deer (Odocoileus hemionus) from Eastern Utah. 1999 Eastern New England Biological Conference.
3. Matt Barth, Jessica Maheux, and Roger Denome. 1999 Genetic Variation in Maine White-Tailed Deer (Odocoileus virginianus). 1999 Eastern New England Biological Conference.
4. Laura Carvalho, Lisa Carvalho, and R.M. Denome. 1997. Genetic variation and differentiation in Rocky Mountain Bighorn sheep in Eastern Utah. 1997 Eastern New England Biological Conference.
5. Denome, R. M. and C. N. Cole. 1987. The effect of multiple polyadenylation signals on polyadenylation site selection. 1987 Cold Spring Harbor meeting on RNA processing.
6. Denome, R. M. and C. N. Cole. 1986. Analysis of the effects of multiple polyadenylation sites on polyadenylation signal usage. 1986 Cold Spring Harbor meeting on RNA processing.
7. Patterson, R. J., J. D. Featherston, R. M. Denome, and E. A. Werner. 1985. Isolated nuclei as a model to study RNA transport. UCLA Symposium on RNA processing.
8. Young, R. B., and R. M. Denome. 1982. Myosin heavy chain metabolism in steady-state embryonic chick muscle cell cultures treated with creatine. J. Cell Bio. 95:374A.
Other publications
1. Jessica Maheux, Matt Barth and Roger Denome. 1999. Genetic variation is White Tail Deer (Odocoileus virginianus) from Eastern North America. Report submitted to Maine game management personnel.
2. Roger Denome, Jenifer Gilbert, and Tamara Palka. 1999. Genetic Variation in Mule Deer (Odocoileus hemionus) from Eastern Utah. Report submitted to Ute Indian tribe of Eastern Utah.
3. Roger M. Denome. 1998. Genetic Variation in North American Populations of Elk (Cervus elaphus). Report Submitted to North Dakota Game and Fish Department and Rocky Mountain Elk Foundation.
4. Szczys. P., B. O'Callaghan, V. Radu, and R.M. Denome. 1995. Population genetics of California Bighorn Sheep (Ovis canadensis californiana) from British Columbia Herds. Report submitted to British Columbia and North Dakota game management personnel.
Consulting in field
Ad Hoc Reviewer, journal Molecular Evolution.
Wildlife genetics advisor to Ute Indian Tribe, Eastern Utah.
Elk genetics advisor for Thief Lake Wildlife Refuge, Thief Lake, Minnesota.
Grants Submitted, Funded or Pending
Pfizer Udergraduate Summer Research Fellowship (for Rebecca Coburn). Assays of Genetic Variation in Coyotes in Massachusetts. $5,000. 1999. Funded.
Summer grant, Stonehill College, Spring 1999, $2150. Support of SURE work. Funded.
Ute Indian Tribal Council, Utah. Mule Deer Herd Health-Genetic Assessmentt. ($1,800), 1998. Funded.
Ute Indian Tribal Council, Utah. Elective Health and Biological Testing of Bighorn Sheep. ($600), 1996. Funded.
Rocky Mountain Elk Foundation. Genetic Evaluation of North Dakota Elk. ($18,000), 1995-1996. Funded.
North Dakota Game and Fish Department grant. Genetic evaluation of California Bighorn Sheep in North Dakota. ($2,500), 1994-1995. Funded.
Foundation for North American Wild Sheep. Genetic variation in California Bighorn Sheep. ($7,360), 1994-1995. Funded.
Professional Activities
Professional Memberships
American Association for the Advancement of Science. (1986-present)
American Society of Microbiologists. (1986-present)
American Society of Mammalogists. (1996-present) Co-coordinator and abstract organizer for 1996 meeting. University of North Dakota, June 1996.
Council on Undergraduate Research. (1998-present)
Attendance at and Organization of Meetings
2000 Eastern New England Biological Conference. April 1999, Merrimack College, North Andover, Massachusetts.
1999 Eastern New England Biological Conference. April 1999, Suffold University, Boston, Massachusetts.
1998 Eastern New England Biological Conference. April 1998, Stonehill College, Easton, Massachusetts (meeting organizer).
1997 Eastern New England Biological Conference. April 1997, Colby-Sawyer College, New London, New Hampshire.
1996 American Society of Mammalogist annual meeting. June 1996, University of North Dakota, Grand Forks, North Dakota (meeting coorganizer, but could not attend).
1986-1993 Cold Spring Harbor meeting on RNA processing. May of each year. Cold Spring Harbor, New York.
Invited lectures
Creation and Evolution. Presented at the Martin Center at invitation of students. March 26, 1997.
DNA. A seminar on the use of DNA fingerprinting and other molecular biology techniques in forensics. Meeting of North Dakota State's Attorneys. February 11, 1994. UND Law school, Grand Forks, North Dakota.
Transcription termination: the end of RNA as we know it. Presented to Moorehead State University Biology Department. April 19, 1994. Moorehead State University, Moorehead, Minnesota.
Work in Progress
Genetic variation in Massachusetts coyote population. Work begun fall 1998, in collaboration with professors Gwilym Jones (Northeastern University) and Ralph Kunkel (Stonehill), Bill Petri (Boston college) and the Watershed Institute of Massachusetts. Unknown date of completion.
Population genetics of striped skunks on islands in Boston Harbor. Work begun fall 1998, in collaboration with professor Ralph Kunkel (Stonehill). Unknown date of completion.
Development of class “Science in the Courtroom”, tentatively to be offered 1999 or 2000.
Pursuit of corporate funding for undergraduate research at Stonehill. Ongoing.
Development of a cooking class for college students. Ongoing.
COLLEGE AND COMMUNITY ACTIVITIES
Seminar coordinator, (Fall 2000-present)
Organizer and member (Saxophone, Guitar), Stonehill Jazz Quintet (Spring 2000-present)
Committees for development of the new general studies curriculum, (1999-2001)
Program on the technology and ethics of genetic modification of humans, Fall 2000, (with Janine
Higgins, residence assistant in the “Sem”)
Community Associate, Fall and Spring 1999.
Pilot program to teach cooking to college students, Spring 1999.
Stonehill Radio panel discussion of Student issues, Spring 1999.
Student/Faculty Discussion forum (in conjunction with Residents Life) to discuss Academic issues, Spring 1999. First meeting discussed faculty and student views on grades and grading.
Standards and Evaluations Committee, Chair, Fall 1998 to present.
Academic Council, Fall 1998 to present (as part of appointment to Standards and Evaluation committee).
Grants Committee, Fall 1999 to present (as part of appointment to Standards and Evaluation committee).
Space Committee, Fall 1998 to present.
College Planning committee, Fall 96/Spring 97.
College Academic committee, Fall 97/Spring 98.
Ad hoc committee on the faculty response to Athletic task force report, 1998.
Development of the Biology Department reading room and library, 1997-present.
Biology Department subcommittee on Major Field Test Analysis, 1997-present.
Faculty advisor to Sigma Zeta national honor society for science (1997-present).
Reviewer of application for Fullbright Scholarship (Spring 1998).
Organizer and co-coordinator of Eastern New England Biological Conference meeting (1998).
Informal coordinator of Science building plan (1997, 1998).
Freshman Orientation (1997, 1998, 1999, 2000).
Commencement Student Assembler (1997, 1998, 1999, 2000).
Coordinator of SURE weekly meetings (Summers 1998, 1999, 2000).
Midnight Breakfast slave (1997, 1998, 1999, 2000).
Occasional participation in and support of the Common Ground Café (Fall 1998-present).
Continuing education class in Evolution for senior citizens (Fall 1997).
Public Debate on the scientific merit of evolutionary theory (Spring 1997).